Estimating basal tear osmolarity in normal and dry eye subjects

نویسندگان
چکیده

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Tear osmolarity and dry eye symptoms in diabetics

PURPOSE To assess the relationship between tear osmolarity and dry eye symptoms in patients with diabetes. PATIENTS AND METHODS Fifty patients with diabetes were enrolled. Demographic information and past medical history were recorded. Symptoms were assessed using the ocular surface disease index (OSDI). Tear osmolarity of each eye was measured with the TearLab® Osmolarity System. RESULTS T...

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Variability of Tear Osmolarity in Patients With Dry Eye.

IMPORTANCE Knowledge about the variability of measurements using the TearLab Osmolarity System is necessary when evaluating the clinical utility of readings. OBJECTIVE To examine the variability of tear osmolarity measured by the TearLab Osmolarity System in patients with Sjögren syndrome (SS), patients with blepharitis, and control participants. DESIGN, SETTING, AND PARTICIPANTS Cross-sect...

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Tear osmolarity as a biomarker for dry eye disease severity.

PURPOSE To study the association between tear osmolarity and dry eye severity grade, based on a modified Dry Eye Workshop (DEWS) scale, and between osmolarity and the signs and symptoms that determine dry eye disease severity. METHODS Nineteen patients with dry eye disease were asked to complete an evaluation of dry eye signs and symptoms composed of the Ocular Surface Disease Index (OSDI) qu...

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A mass and solute balance model for tear volume and osmolarity in the normal and the dry eye.

Tear hyperosmolarity is thought to play a key role in the mechanism of dry eye, a common symptomatic condition accompanied by visual disturbance, tear film instability, inflammation and damage to the ocular surface. We have constructed a model for the mass and solute balance of the tears, with parameter estimation based on extensive data from the literature which permits the influence of tear e...

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Tear osmolarity in the diagnosis and management of dry eye disease.

PURPOSE To evaluate the use of tear osmolarity in the diagnosis of dry eye disease. DESIGN A prospective, observational case series to determine the clinical usefulness of tear osmolarity and commonly used objective tests to diagnose dry eye disease. METHODS A multicenter, 10-site study consisting of 314 consecutive subjects between 18 and 82 years of age. Bilateral tear osmolarity, tear fi...

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ژورنال

عنوان ژورنال: Contact Lens and Anterior Eye

سال: 2018

ISSN: 1367-0484

DOI: 10.1016/j.clae.2017.09.005